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Scientists discover key genetic factors behind testicular cancer

Scientists have identified new gene faults and evolutionary patterns contributing to testicular cancer. Their findings offer profound insights into the development of the disease and into potential treatment strategies.

14 Nov 2024

Study shows how microbial load affects gut health and disease

In sickness or in health, the billions of microorganisms that inhabit our guts are our constant companions throughout life. In the past few decades, scientists have shown how the nature of this 'microbiome' can provide valuable clues to human diseases and their treatment.

14 Nov 2024

MaxCyte celebrates 25 years of innovation driving cell engineering-based therapeutics

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell therapeutics, marks the 25th anniversary of its founding this year.

From MaxCyte, Inc. 13 Nov 2024

Metagenomic sequencing improves detection of rare pathogens in CNS infections

New research shows that metagenomic next-generation sequencing (mNGS) over seven years increased pathogen detection in challenging CNS infections, identifying rare and unexpected microbes often missed by standard testing.

13 Nov 2024

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Professor Nancy Ip discusses her groundbreaking neuroscience research, focusing on neurotrophic factors and innovative Alzheimer's disease treatment approaches.

13 Nov 2024

MassiveFold advances protein structure prediction with efficient parallel processing

Researchers developed MassiveFold, an enhanced AlphaFold version optimized for parallel processing, which accelerates protein structure predictions from months to hours while increasing structural diversity.

12 Nov 2024

Study provides new insights into the central role of goblet cells

In a recent study, researchers at the University of California, San Diego, have provided new insights into the central role of goblet cells-;specialized cells that line the gut-;in maintaining a healthy and balanced immune environment within the gastrointestinal (GI) tract.

12 Nov 2024

Vitamin D receptor activation slows cell overgrowth in pulmonary hypertension

The study demonstrates that activating the vitamin D receptor (VDR) with calcitriol suppresses cell proliferation in pulmonary arterial smooth muscle cells, potentially reducing disease severity in pulmonary arterial hypertension (PAH).

12 Nov 2024

Georgia Tech researchers create lab-grown models of human immune systems

To better understand why some cancer patients struggle to fight off infections, Georgia Tech researchers have created tiny lab-grown models of human immune systems.

12 Nov 2024

Early genomic profiling improves cancer treatment outcomes

New real-world data from Providence, Illumina, and Microsoft Research reveals that Comprehensive Genomic Profiling (CGP), when done early in a cancer patient's diagnosis, leads to better personalized treatment and patient outcomes.

12 Nov 2024

Novel compound BHB-Phe could offer new approach to weight loss

Researchers at Baylor College of Medicine, Stanford University School of Medicine and collaborating institutions report in the journal Cell the discovery of BHB-Phe, a novel compound produced by the body that regulates appetite and body weight through interactions with neurons in the brain.

12 Nov 2024

Researchers unlock method for mass producing herbal medicine in yeast

Herbal medicine is difficult to produce on an industrial scale. A team of Kobe University bioengineers manipulated the cellular machinery in a species of yeast so that one such molecule can now be produced in a fermenter at unprecedented concentrations.

12 Nov 2024

Metabolic enzymes take on unexpected roles in cell division and DNA repair

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, orchestrating critical functions like cell division and DNA repair.

12 Nov 2024

Next-generation metagenomic sequencing test quickly detects any kind of pathogen

Next-generation metagenomic sequencing test developed at UCSF proves its effectiveness in quickly diagnosing almost any kind of pathogen.

12 Nov 2024

New study highlights the importance of BMI in disease pathogenesis

New study from deCODE genetics/Amgen highlights the importance of BMI in pathogenesis of disease, suggesting that reducing BMI alone could lower the risk of several diseases.

12 Nov 2024

Neuropeptides influence T cell differentiation during viral infections

T helper (TH) cells are essential immune cells that help other immune cells function effectively. When activated in response to environmental stimuli, these cells can differentiate into either TH1 cells, which fight against viruses and intracellular pathogens, or TH2 cells, which fight against extracellular pathogens like bacteria and parasites.

12 Nov 2024

Mitochondria’s division of labor sheds light on how cancer cells survive harsh conditions

Research shows mitochondria form distinct subpopulations under nutrient stress, revealing survival mechanisms in cancer cells and potential therapeutic targets.

12 Nov 2024

Nomic® and Parker Institute for Cancer Immunotherapy (PICI) launch large-scale protein profiling to investigate immunotherapy responses in RADIOHEAD study

Nomic Bio and PICI collaborate to quantify protein biomarkers in cancer immunotherapy, enhancing understanding of patient responses and treatment resistance.

From Nomic 12 Nov 2024

Study shows how a single defective BRCA1 gene accelerates cancer development

People inherit two copies of each gene -; one from each parent -; an evolutionary fail-safe to ensure survival even when one of them doesn't function.

11 Nov 2024

New genetic model offers insights into breast cancer metastasis

A Michigan State University researcher's new model for studying breast cancer could help scientists better understand why and where cancer metastasizes.

11 Nov 2024